Signs of gold fish disease are ragged or blood streaked fins, loss of balance, unusual swimming action or cotton wool-like growths, slimy white skin or fins, cloudy eyes, white spots, lying on the bottom of the tank, gasping at the surface of the water, clamped fins or loss of appetite. Disease Safe is simple to use; measure the volume of your tank, bowl or orb and add the correct dose using the supplied pipette or cap. One pipette treats 0.57 litres and one capfull will treat 2.65 litres. Disease Safe can be re-dosed if your fish have not recovered after five days. Follow supplied the instructions carefully.